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Publications

Journal articles

  1. E. M. Hilton, M. A. Jinks, A. D. Burnett, N. J. Warren,* A. J. Wilson*: Visible-light driven multistate assembly of hydrogen bonding foldamers, ChemRxiv, 2023, 10.26434/chemrxiv-2023-lpp8t . View Paper.
  2. E. E. Cawood, E. Baker, T. A. Edwards, D. N. Woolfson,* T. K. Karamanos,* A. J. Wilson*: Peptidomimetic inhibitors of β-strand-mediated protein-protein interactions: tuning binding affinity of intrinsically disordered sequences through backbone modification, ChemRxiv, 2023, 10.26434/chemrxiv-2023-xglb4 . View Paper.
  3. P. Zhang, M. Walko, A. J. Wilson*: Maleimide constrained BAD BH3 domain peptides as BCL-xL Inhibitors: A Versatile Approach to Rapidly Identify Sites Compatible with Peptide Constraining, Bioorg. Med. Chem. Lett., 2023, 87, 129260. View Paper.
  4. P. Zhang, M. Walko, A. J. Wilson*: Rational Design of Harakiri (HRK)-Derived Constrained Peptides as BCL-xL inhibitors , Chem. Commun., 2023, 59, 1697-1700. View Paper.
  5. J. S. Pallesen, C. C. Munier, F. Bosica, S. A. Andrei, K. Edman, A. Gunnarsson, G. La Sala, O. Dwichandra Putra, S. Srdanović, A. J. Wilson, L. Wissler, C. Ottmann, M. W. D. Perry, Gavin O’Mahony*: Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3-3 Protein–Protein Interaction, J. Med. Chem. , 2022, 65, 16818-16828. View Paper. Correction.
  6. M. A. Jinks, M. Howard, F. Rizzi, S. M. Goldup, A. D. Burnett, A. J. Wilson*: Direct Detection of Hydrogen Bonds in Supramolecular Systems Using 1H-15N Heteronuclear Multiple Quantum Coherence Spectroscopy, J. Am. Chem. Soc., 2022, 50, 23127-23133. View Paper.
  7. S. Srdanović, Z. Hegedüs, S. L. Warriner, A. J. Wilson*: Towards Identification of Protein-Protein Interaction Stabilizers via Inhibitory Peptide-Fragment Hybrids Using Templated Fragment Ligation, RSC Chem. Biol., 2022, 3, 546-550. View Paper.
  8. F. Hóbor, Z. Hegedüs, A. A. Ibarra, V. L. Petrovicz, G. J. Bartlett, R. B. Sessions, A. J. Wilson*, T. A. Edwards*: Understanding p300-transcription factor interactions using sequence variation and hybridization, RSC Chem. Biol., 2022, 3, 562-603. View Paper.
  9. S. Srdanović, M. Wolter, C. H. Trinh, C. Ottmann, S. L. Warriner, A. J. Wilson*: Understanding the interaction of 14-3-3 proteins with hDMX and hDM2: a structural and biophysical study, FEBS J,, 2022, 289, 5341-5358. View Paper.
  10. M. Batchelor, R. S. Dawber, A. J. Wilson*, R. Bayliss*: α-Helix stabilization by co-operative side chain charge-reinforced interactions to phosphoserine in a basic kinase-substrate motif, Biochem J., 2022, 479, 687-700. View Paper.
  11. K. Hetherington, S. Dutt, A. A. Ibarra, E. E. Cawood, F. Hóbor, D. N. Woolfson, T. A. Edwards, A. Nelson, R. B. Sessions,* A. J. Wilson*: Towards optimizing peptide-based inhibitors of protein–protein interactions: predictive saturation variation scanning (PreSaVS), RSC Chem. Biol., 2021, 2, 1474-1478. View Paper.
  12. T. Ueda, T. Tamura, M. Kawano, K. Shiono, F. Hobor, A. J. Wilson, I. Hamachi*: Enhanced suppression of a protein-protein interaction in cells using small-molecule covalent inhibitors based on N-acyl-N-alkyl sulfonamide warhead, J. Am. Chem. Soc. , 2021, 143, 4766-4774. View Paper.
  13. H. Wang, R. Dawber, P. Zhang, M. Walko, A. J. Wilson,* X. Wang*: Peptide-Based Inhibitors of Protein-Protein Interactions: Biophysical, Structural and Cellular Consequences of Introducing a Constraint , Chem. Sci., 2021, 12, 5977-5993. View Paper.
  14. S. Celis, F. Hóbor, T. James, G. J. Bartlett, A. A. Ibarra, D. K. Shoemark, Z. Hegedüs, K. Hetherington, D. N. Woolfson, R. B. Sessions, T. A. Edwards, D. M. Andrews,* A. Nelson,* A. J. Wilson*: Query-Guided Protein-Protein Interaction Inhibitor Discovery, Chem. Sci., 2021, 12, 4753-4762. View Paper.
  15. B. Zhang, Y. Wang, H. Li, X. Wang, Y. Peng, K. S. Mineev, A. J. Wilson, H. Wang,* X. Wang*: Targeting the Transmembrane Domain 5 of Latent Membrane Protein 1 Using Small Molecule Modulators, Eur. J. Med. Chem., 2021, 113210. View Paper.
  16. Z. Hegedüs, F. Hóbor, D. K Shoemark, L.-Y. Lian, C. Trinh, R. B. Sessions, T. A. Edwards, A. J. Wilson*: Identification of β-Strand Mediated Protein-Protein Interaction Inhibitors Using Ligand-Directed Fragment Ligation, Chem. Sci., 2021, 12, 2286-2293. View Paper.
  17. E. E. Cawood, T. K. Karamanos, A. J. Wilson,* S. E. Radford*: Visualizing and trapping transient oligomers in amyloid assembly pathways, Biophys. Chem., 2021, 268, 106505. View Paper.
  18. J. A. Miles, F. Hóbor, C. H, Trinh, J. Taylor, C. Tiede, P. R. Rowell, B. R. Jackson, F. A. Nadat, P. Ramsahye, H. F. Kyle, B. I. M. Wicky, J. Clarke, D. C. Tomlinson, A. J. Wilson,* T. A. Edwards*: Selective Affimers Recognize the BCL‐2 Family Proteins BCL‐xL and MCL‐1 through Non‐Canonical Structural Motifs, ChemBioChem, 2021, 22, 232-240. View Paper.
  19. A. Lindsey‐Crosthwait, D. Rodriguez‐Lema, M. Walko C. M. Pask, A. J. Wilson*: Structural optimization of reversible dibromomaleimide peptide stapling, Pept. Sci., 2021, 113, e24157. View Paper.
  20. E. E. Cawood, N. Guthertz, J. Ebo, T. K. Karamanos, S. E. Radford,* A. J. Wilson*: Modulation of amyloidogenic protein self-assembly using tethered small molecules, J. Am. Chem. Soc., 2020, 142, 20845-20854. View Paper.
  21. S. J. Bunce, Y. Wang, S. E. Radford, A. J. Wilson, C. K. Hall*: Structural insights into peptide self-assembly using photo-induced crosslinking experiments and discontinuous molecular dynamics , AIChE Journal, 2020, e17101. View Paper.
  22. M. Wolter, P. de Vink, J. F. Neves, S. Srdanović, Y. Higuchi, N. Kato, A. J. Wilson, I. Landrieu, L. Brunsveld, C. Ottmann*: Selectivity via Cooperativity: Preferential Stabilization of the p65/14-3-3 interaction with Semi-Synthetic Natural Products., J. Am. Chem. Soc., 2020, 142, 11772–11783. View Paper.
  23. A. Green, F. Hobor, C. Tinworth, S. L. Warriner, A. J. Wilson, A. Nelson*: Activity‐directed synthesis of inhibitors of the p53/hDM2 protein‐protein interaction, Chem. Eur. J., 2020, 26, 10682-10689 . View Paper.
  24. A.N. Calabrese, B. Schiffrin, M. Watson, T.K. Karamanos, M. Walko, J.R. Humes, J.E. Horne, P. White, A.J. Wilson, A.C. Kalli, R. Tuma, A.E. Ashcroft, D.J. Brockwell, S E. Radford*: Inter-domain dynamics in the chaperone SurA and multi-site binding to its outer membrane protein clients, Nat. Commun., 2020, 11, 2155. View Paper.
  25. K. Hetherington, Z. Hegedüs, T. A Edwards; R. B. Sessions; A. Nelson; A. J. Wilson*: Stapled Peptides as HIF-1α/p300 Inhibitors: Helicity Enhancement in the Bound State Increases Inhibitory Potency, Chem. Eur. J., 2020, 26, 7638-7646. View Paper.
  26. H. M. Coubrough, M. Reynolds, J. A. Goodchild, S. D. A. Connell, J. Mattsson, A. J. Wilson*: Assembly of Miscible Supramolecular Network Blends Using DDA·AAD Hydrogen-Bonding Interactions of Pendant Side-Chains, Poly. Chem., 2020, 11, 3593-3604. View Paper.
  27. C. W. Wood, A. A. Ibarra, G. J. Bartlett, A. J. Wilson, D. N. Woolfson, R. B. Sessions*: BAlaS: fast, interactive and accessible computational alanine-scanning using BudeAlaScan, Bioinformatics, 2020, 36, 2917–2919 . View Paper.
  28. H. M. Coubrough, B. Balonova, C. M. Pask, B. A. Blight, A. J. Wilson*: A pH-Switchable Triple Hydrogen-Bonding Motif , ChemistryOpen, 2020, 9, 40-44. View Paper.
  29. H. A. Beard, J. R. Hauser, M. Walko, R. M. George, A. J. Wilson,* R. S. Bon*: Photocatalytic proximity labelling of MCL-1 by a BH3 ligand, Comms. Chem., 2019, 2, 133. View Paper.
  30. A. A. Ibarra, G. J. Bartlett, Z. Hegedüs, S. Dutt, F. Hóbor, K. A. Horner, K. Hetherington, K. Spence, A. Nelson, T. A Edwards, D. N. Woolfson, R. B. Sessions,* A. J. Wilson*: Predicting and Experimentally Validating Hot-spot Residues at Protein-Protein Interfaces, ACS Chem. Biol., 2019, 14, 2252-2263. View Paper.
  31. Y. Wang, Y. Peng, B. Zhang, X. Zhang, H. Li, A. J. Wilson, K. S. Mineev, X. Wang*: Targeting trimeric transmembrane domain 5 of oncogenic latent membrane protein 1 using a computationally designed peptide, Chem. Sci., 2019, 10, 7584-7590. View Paper.
  32. S. J. Bunce, Y. Wang, K. L. Stewart, A. E. Ashcroft, S. E. Radford,* C. K. Hall,* A. J. Wilson*: Molecular Insights into the surface catalyzed secondary nucleation of Amyloid-β40 (Aβ40) by the peptide fragment Aβ16-22, Sci. Adv., 2019, 5, eaav8216. View Paper.
  33. I. Arrata, C. M. Grison, H. M. Coubrough, P. Prabhakaran, M. A. Little, D. C. Tomlinson, M. E. Webb, A. J. Wilson*: Control of Conformation in α-Helix Mimicking Aromatic Oligoamide Foldamers Through Interactions Between Adjacent Side-Chains, Org. Biomol. Chem., 2019, 17, 3861-3867. View Paper.
  34. M. Walko, E. Hewitt, S. E. Radford, A. J. Wilson*: Design and Synthesis of Cysteine-Specific Labels for Photo-Crosslinking Studies , RSC Adv., 2019, 9, 7610-7614. View Paper.
  35. Z. Hegedus, C. M. Grison, J. A. Miles, S. Rodriguez-Marin, S. L. Warriner, M. E. Webb, A. J. Wilson*: A Catalytic Protein–Proteomimetic Complex: Using Aromatic Oligoamide Foldamers as Activators of RNase S, Chem. Sci., 2019, 10, 3956-3962. View Paper.
  36. Y. Wang, S. Bunce, S. E. Radford, A. J. Wilson, S. Auer, C. K. Hall*: Thermodynamic Phase Diagram of Amyloid-β (16-22) Peptide, Proc. Natl. Acad. Sci. USA, 2019, 116, 2091-2096. View Paper.
  37. M. Bakail, S. Rodriguez-Marin, Z. Hegedüs, M. E. Perrin, F. Ochsenbein*, A. J. Wilson*: Recognition of ASF1 Using Hydrocarbon Constrained Peptides, ChemBioChem, 2019, 20, 891-895. View Paper.
  38. F, H. dos Santos Rodrigues, H. Firczuk, A, L Breeze, A. D. Cameron, M. Walko, A. J. Wilson, N. I. T. Zanchin, J. E. G. McCarthy*: The Leishmania PABP1–eIF4E4 Interface: a Novel 5′–3′ Interaction Architecture for Trans-Spliced mRNAs, Nucleic Acids Res., 2019, 47, 1493-1504. View Paper.
  39. H. Coubrough S. van der Lubbe K. Hetherington A. Minard, C. Pask M. Howard C. Fonseca Guerra,* A. J. Wilson*: Supramolecular Self‐Sorting Networks Using Hydrogen‐Bonded Motifs, Chem. Eur. J., 2019, 25, 785 –795. View Paper.
  40. J. E. Horne, M. Walko, A. N. Calabrese, M. A. Levenstein, D. J. Brockwell, N. Kapur, A. J. Wilson*, S. E. Radford*:Rapid Mapping of Protein Interactions Using Tag-Transfer Photocrosslinkers, Angew. Chemie. Int. Ed., 2018, 57, 16688–16692. View Paper.
  41. J. M. Fletcher, K. A. Horner, G. J Bartlett, G. R. Rhys, A. J. Wilson,* D. N. Woolfson*: De novo coiled-coil peptides as scaffolds for disrupting protein-protein interactions, Chem. Sci., 2018, 9, 7656-7665. View Paper.
  42. G. Cui, V. A. H. Boudara, Q. Huang, G. P. Baeza, A. J. Wilson, O. Hassager, D. J. Read, J. Mattsson*: Linear shear and nonlinear extensional rheology of unentangled supramolecular side-chain polymers, J. Rheol., 2018, 62, 1155-1174. View Paper.
  43. S. H. Hewitt, A. J. Wilson*: Generation of Dynamic Combinatorial Libraries Using Hydrazone Functionalized Surface Mimetics, Eur. J. Org. Chem., 2018, 1872-1879. View Paper.
  44. L. M. Stevers, E. Sijbesma, M. Botta, C. MacKintosh, T. Obsil, I. Landrieu, Y. Cau, A. J. Wilson, A. Karawajczyk, J. Eickhoff, J. Davis, M. Hann, G.O’Mahony, R. G. Doveston, L. Brunsveld, C. Ottmann*: Modulators of 14-3-3 Protein–Protein Interactions, J. Med. Chem. , 2018, 61, 3755-3778. View Paper.
  45. S. H. Hewitt, A. J. Wilson*: Protein Sensing and Discrimination Using High Functionalised Ruthenium (II) tris(Bipyridyl) Protein Surface Mimetics in an Array Format, Chem. Commun., 2017, 53, 12278-12281. View Paper.
  46. C. M. Grison, G. M. Burslem, J. A . Miles, L. K. A. Pilsl, D. J. Yeo, Z. Imani, S. L. Warriner, M. E. Webb, A. J. Wilson*: Double Quick, Double Click Reversible Peptide “Stapling”, Chem. Sci., 2017, 8, 5166-5171. View Paper.
  47. G. M. Burslem, H. F. Kyle, A. Nelson, T. A. Edwards, A. J. Wilson*: Hypoxia inducible factor (HIF) as a model for studying inhibition of protein–protein interactions , Chem. Sci., 2017, 8, 4188-4202. View Paper. Correction. Correction to Correction. Further Correction.
  48. I. Arrata, A. Barnard, D. C. Tomlinson, A. J. Wilson*:Interfacing Native and Non Native Peptides: Using Affimers to Recognise α-Helix Mimicking Foldamers, Chem. Commun., 2017, 53, 2834-2837. View Paper.
  49. S. H. Hewitt, M. H. Filby, E. Hayes, L. T. Kuhn, A. P. Kalverda, M. E. Webb, A. J. Wilson*: Protein surface mimetics: understanding how ruthenium tris(bipyridines) interact with proteins, ChemBioChem, 2017, 18, 223-231. View Paper.
  50. C.M. Grison, J. A. Miles, S. Robin, A. J. Wilson*, D. J. Aitken*: An a-Helix-Mimicking 12,13-Helix: Designed α/β/γ-Foldamers as Selective Inhibitors of Protein–Protein Interactions, Angew. Chem. Int. Ed. , 2016, 55, 11096–11100 . View Paper.
  51. S. H. Hewitt, A. J. Wilson*: Metal complexes as “Protein Surface Mimetics”, Chem. Commun., 2016, 52, 9745-9756. View Paper. Correction.
  52. G. M. Burslem, H. F. Kyle, P. Prabhakaran, A. L. Breeze, T. A. Edwards, A. S. Nelson, S. L. Warriner, A. J. Wilson*: Synthesis of Highly Functionalized Oligobenzamide Proteomimetic Foldamers by Late Stage Introduction of Sensitive Groups, Org. Biomol. Chem., 2016, 14, 3782-3786. View Paper.
  53. G. M. Burslem, H. F. Kyle, A. L. Breeze, T. A. Edwards, A. S. Nelson, S. L. Warriner, A. J. Wilson*: Towards “Bionic” Proteins: Replacement of Continuous Sequences from HIF-1α with Proteomimetics to Create Functional p300 Binding HIF-1α Mimics, Chem. Commun., 2016, 52, 5421-5424. View Paper.
  54. J. A. Miles, D. J. Yeo, Philip Rowell, S. Rodriguez-Marin, C. M. Pask, S. L. Warriner, T. A. Edwards*, A. J. Wilson*: Hydrocarbon Constrained Peptides – Understanding Preorganization and Binding Affinity, Chem. Sci., 2016, 7, 3694-3702. View Paper.
  55. L.-J. Liu, B. He, W. I. Che, Z. Mao, J.-J. Lu, X.-P. Chen, J. A. Miles, A. J. Wilson, D.-L. Ma*, C.-H. Leung*: Inhibition of the p53/hDM2 protein-protein interac-tion by cyclometallated iridium(III) compounds , Oncotarget, 2016, 7, 13965-13975. View Paper.
  56. V. Azzarito, P. Rowell, A. Barnard, T. A. Edwards, A. Macdonald, S. L. Warriner*, A. J. Wilson*:Probing Protein Surfaces: QSAR Analysis using Helix Mimetics, ChemBioChem, 2016, 17, 768-773. View Paper.
  57. S. Rodriguez-Marin, N. S. Murphy, H. J. Shepherd, A.J. Wilson*: Design, Synthesis and Conformational Analyses of Bifacial Benzamide Based Foldamers, RSC Adv., 2015, 5, 104187-104192. View Paper.
  58. H. F. Kyle, K. F. Wickson, J. Stott, G. M. Burslem, A. L. Breeze, C. Tiede, D. C. Tomlinson, S. L. Warriner, A. Nelson, A. J. Wilson, T. A. Edwards*: Exploration of the HIF-1α/p300 interface using peptide and Adhiron phage display technologies, Mol. BioSys., 2015, 11, 2738-2749. View Paper.
  59. A. J. Wilson*: Helix Mimetics: Recent Developments, Prog. Biophys. Mol. Bio., 2015, 119, 33-40. View Paper.
  60. K. A. Houton, G. M. Burslem, A. J. Wilson*: Development of Solvent-Free Synthesis of Hydrogen-Bonded Supramolecular Polyurethanes, Chem. Sci., 2015, 6, 2382-2388. View Paper.
  61. V. Azzarito, J. A. Miles, J. Fisher, T. A. Edwards, S. L. Warriner, A. J. Wilson*: Stereocontrolled Protein
    Surface Recognition Using Chiral Oligoamide Proteomimetic Foldamers,     Chem. Sci., 2015, 6, 2434-2443. View Paper.
  62. A. Barnard, K. Long, H. L. Martin, J. A. Miles, T. A. Edwards, D. C. Tomlinson, A. Macdonald,* A. J. Wilson*: Selective and Potent Proteomimetic Inhibitors of Intracellular Protein-Protein Interactions, Angew. Chem. Int. Ed. , 2015, 54, 2960-2965. View Paper.
  63. A. Barnard, J. A. Miles, G. M. Burslem, A. M. Barker, A. J. Wilson*: Multivalent Helix Mimetics for PPI-Inhibition, Org. Biomol. Chem., 2015, 13, 258-264. View Paper.
  64. K. A. Houton, A. J.Wilson*: Hydrogen-Bonded Supramolecular Polyurethanes, Polym. Int., 2015, 64, 165-173. View Paper.
  65. A. Barnard, K. Long, D. J. Yeo, J. A. Miles, V. Azzarito, G. M. Burslem, P. Prabhakaran, T. A. Edwards, A. J. Wilson*: Orthogonal Functionalisation of α-Helix Mimetics, Org. Biomol. Chem., 2014, 12, 6794-6799. View Paper.
  66. G. M. Burslem, H. F. Kyle, A. L. Breeze, T. A. Edwards, A. S. Nelson, S. L. Warriner, A. J. Wilson*: Small Molecule Proteomimetic Inhibitors of the HIF-1α/p300 Protein-Protein Interaction, ChemBioChem, 2014, 15, 1083-1087. View Paper.
  67. G. Preston, S. E. Radford, A. E. Ashcroft, A. J. Wilson*: Analysis of Amyloid Nanostructures Using Photo-Crosslinking: In Situ Comparison of Three Widely Used Photo-Crosslinkers, ACS Chem. Biol., 2014, 9, 761–768. View Paper.
  68. G. M. Burslem, A. J. Wilson*: Synthesis of Oligobenzamide α-Helix Mimetics, Synlett, 2014, 25, 324-335. View Paper.
  69. A. Gooch, N. S. Murphy, N. Thomson, A. J. Wilson*: Side-Chain Supramolecular Polymers Employing Conformer Independent Triple Hydrogen Bonding Arrays, Macromolecules, 2013, 46, 9634–9641. View Paper.
  70. D. J. Yeo, S. L. Warriner, A. J. Wilson*:Monosubstituted Alkenyl Amino Acids for Peptide “Stapling”, Chem. Commun., 2013, 49, 9131-9133. View Paper.
  71. P. Prabhakaran, A. Barnard, N. S. Murphy, C. A. Kilner, T. A. Edwards, A. J. Wilson*: Aromatic oligoamide foldamers with a "wet edge" as inhibitors of the helix mediated p53-hDM2 protein-protein interaction, Eur. J. Org. Chem., 2013, 17, 3504-3512. View Paper.
  72. M. L. Pellizzaro, K. A. Houton, A. J. Wilson*:Sequential and Phototriggered Supramolecular Self-Sorting Cascades Using Hydrogen-Bonded Motifs, Chem. Sci., 2013, 4, 1825-1829. View Paper.
  73. A. J. Wilson,* J. R. Ault, M. H. Filby H. I. A. Philips, A. E. Ashcroft, N, C. Fletcher: Protein Destabilisation by Ruthenium(II) Tris-Bipyridine Based Protein-Surface Mimetics, Org. Biomol. Chem., 2013, 11, 2206-2212. View Paper.
  74. N. S. Murphy, P. Prabhakaran, V. Azzarito, J. P. Plante, M. J. Hardie, C. A. Kilner, S. L. Warriner, A. J. Wilson*: Solid Phase Methodology for Synthesis of O-Alkylated Aromatic Oligoamide Inhibitors of α-helix Mediated Protein-Protein Interactions, Chem. Eur. J., 2013, 19, 5546-5550. View Paper.
  75. G. Preston, A. J. Wilson*: Photo-induced covalent cross-linking for the analysis of biomolecular interactions, Chem. Soc. Rev., 2013, 42, 3289-3301. View Paper.
  76. M. L. Pellizzaro, J. Fisher, A. J. Wilson*:Electronic Substituent Effects on Hydrogen-Bonding Motifs Modulate Supramolecular Polymerisation, RSC Adv., 2013, 3, 3103 - 3108. View Paper.
  77. V Azzarito, K. Long, N. S. Murphy and A. J. Wilson*: Inhibition of a-Helix Mediated Protein-Protein Interactions Using Designed Molecules, Nature Chem., 2013, 5, 161-173. View Paper.
  78. K. Long, T. A. Edwards, A. J. Wilson*: Microwave assisted solid phase synthesis of highly functionalized N-alkylated oligobenzamide a-helix mimetics, Bioorg. Med. Chem., 2013, 21, 4034-4040 . View Paper.
  79. H. I. A. Phillips, A. V. Chernikov, N. C. Fletcher,* A. E. Ashcroft, J. R. Ault, M. H. Filby, A. J. Wilson: The Use of Electrospray Mass spectrometry to Determine Speciation in a Dynamic Combinatorial Library for Anion Recognition, Chem. Eur. J., 2012, 18, 13733-13742. View Paper.
  80. J. C. Fuller, T. A. Edwards, A. J. Wilson, R. M. Jackson, M. R. Shirts*: Modeling of Arylamide Helix Mimetics in The p53 Peptide Binding Site of hDM2 Supports the Putative Binding Location and Suggests Parallel and Anti-parallel Conformations are Both Stable, PLoS ONE, 2012, 7, e43253. View Paper.
  81. V. Azzarito, P. Prabhakaran, A. I. Bartlett, N. S. Murphy, M. J. Hardie, C. A. Kilner, T. A. Edwards, S. L. Warriner, A. J. Wilson*:2-O-Alkylated Para-Benzamide a-Helix Mimetics: The Role of Scaffold Curvature, Org. Biomol. Chem., 2012, 10, 6469-6472. View Paper.
  82. G. Preston, S. E. Radford, A. E. Ashcroft, A. J. Wilson*:Covalent cross-linking within supramolecular peptide structures, Anal. Chem., 2012, 84, 6790–6797. View Paper.
  83. A. Gooch, C. Nedolisa, K. Houton, C. I. Lindsay, A. Saiani, A. J. Wilson*: Tuneable Self-Assembled Elastomers Using Triply Hydrogen-Bonded Arrays, Macromolecules, 2012, 45, 4723-4729. View Paper.
  84. M. Pellizzaro, S. Barrett, J. Fisher, A. J. Wilson*:Design, Synthesis and Binding Studies of a Novel Quadruple ADDA Hydrogen-Bond Array, Org. Biomol. Chem., 2012, 10, 4899-4906. View Paper.
  85. S. J. Turrell, M. H. Filby, A, Whitehouse, A. J. Wilson*: Cellular Uptake of Highly-Functionalized Ruthenium(II) tris-Bipyridine Protein-Surface Mimetics, Bioorg. Med. Chem. Lett., 2012, 22, 985-988 . View Paper.
  86. P. Prabhakaran, V. Azzarito, T. Jacobs, M. J. Hardie, C. A. Kilner, T. A. Edwards, S. L. Warriner, A. J. Wilson*:Conformational Properties of O-alkylated Benzamides, Tetrahedron , 2012, 68, 4485-4491 . View Paper.
  87. M. L. Pellizzaro, A. M. McGhee, L. C. Renton, M. G. Nix, J. Fisher, W. B. Turnbull, A. J. Wilson*:Conformer Independent Ureidoimidazole Motifs: Tools to Probe Conformational and Tautomeric effects on the Molecular Recognition of Triply Hydrogen-Bonded Heterodimers, Chem. Eur. J., 2011, 17, 14508-14517. View Paper.
  88. A. Gooch, S. Barrett, J. Fisher, C. I. Lindsay, A. J. Wilson*: Ditopic Triply Hydrogen-Bonded Heterodimers, Org. Biomol. Chem., 2011, 9, 5938-5940. View Paper.
  89. T. A. Edwards, A. J. Wilson*: Helix Mediated Protein-Protein Interactions as Targets for Intervention Using Foldamers, Amino Acids, 2011, 41, 743-754. View Paper.
  90. A. M. McGhee, J. P. Plante, C. A. Kilner, A. J. Wilson*: Solid State Structures of Ureidoimidazoles, Supramol. Chem., 2011, 23, 470-480. View Paper.
  91. M. H. Filby, J. Muldoon, S. Dabb, N. C. Fletcher, A. E. Ashcroft, A. J. Wilson*: Protein surface recognition using geometrically pure Ru(II) tris(bipyridine) derivatives, Chem. Commun., 2011, 559-561 (PMC3172587). View Paper.
  92. A. Gooch, A. M. McGhee, M. L. Pellizzaro, C. I. Lindsay, A. J. Wilson*: Substituent Control over Dimerization Affinity of Triply Hydrogen-Bonded Heterodimers, Org. Lett., 2011, 13, 240-243. View Paper.
  93. F. Campbell, J. P. Plante, T. A. Edwards*, S. L. Warriner*, A. J. Wilson*: N-Alkylated Oligoamide alpha-Helical Proteomimetics, Org. Biomol. Chem., 2010, 8, 2344-2351. View Paper.
  94. F. Campbell, C. A. Kilner, A. J. Wilson*: Expedient Synthesis of Benzene Tricarboxamide Macrocycles Derived from p-Aminobenzoic Acid, Tetrahedron Lett., 2010, 51, 1361-1363. View Paper.
  95. J. Muldoon, A. E. Ashcroft, A. J. Wilson*: Selective Protein-Surface Sensing Using Ruthenium(II) Tris-(Bipyridine) Complexes, Chem. Eur. J., 2010, 16, 100-103 (PMID: 19946912). View Paper.
  96. A.J.Wilson*: Inhibition of Protein-Protein Interactions Using Designed Molecules , Chem. Soc. Rev., 2009, 38, 3289-3300. View Paper.
  97. J. P. Plante, T. Burnley, B. Malkova, M. E. Webb, S. L. Warriner, T. A. Edwards,* A. J. Wilson*: Oligobenzamide Proteomimetic Inhibitors of the p53-hDM2 Protein-Protein Interaction, Chem. Commun., 2009, 5091-5093. View Paper.
  98. A. Gooch, A. M. McGhee, L. C. Renton, J. P. Plante, C. I. Lindsay, A. J. Wilson*: Synthesis and Binding Properties of Conformer-Independent Linear ADA Hydrogen-Bonding Arrays, Supramol. Chem., 2009, 21, 12-17. View Paper.
  99. F. Campbell, A. J. Wilson*: An ‘Impossible’ Macrocyclisation Using Conformation Directing Protecting Groups, Tetrahedron Lett., 2009, 50, 2236-2238. View Paper.
  100. D. P. Smith, J. Anderson, J. Plante, A. E. Ashcroft, S. E. Radford, A. J. Wilson,* M. J. Parker*: Trifluoromethyldiazirine: an Effective Photo-induced Cross-linking Probe for Exploring Amyloid Formation, Chem. Commun., 2008, 5728. View Paper.
  101. J. Plante, F. Campbell, B. Malkova, C. Kilner, S. L Warriner, A. J. Wilson*: Synthesis of Functionalised Aromatic Oligamide Rods, Org. Biomol. Chem. , 2008, 6, 138-146 (PMID: 18075658). View Paper.
  102. A. M. McGhee, C. Kilner, A. J. Wilson*: Conformer Independent Heterodimerisation of Linear Arrays Using Three Hydrogen Bonds, Chem. Commun., 2008, 344-346. View Paper.
  103. F. Campbell, J. Plante, C. Carruthers, M. J. Hardie, T. J. Prior, A. J. Wilson*: Macrocyclic Scaffolds Derived From Para-Aminobenzoic Acid, Chem. Commun., 2007, 2240-2242. View Paper.
  104. A.J.Wilson*: Non-Covalent Polymer Assembly Using Arrays of Hydrogen-Bonds, Soft Matter, 2007, 3, 409-425. View Paper.
  105. A. J. Wilson, J. Hong, S. Fletcher, A. D. Hamilton*: Recognition of Solvent Exposed Protein Surfaces Using Anthracene Derived Receptors, Org. Biomol. Chem., 2007, 5, 276-285. View Paper.
  106. A. J. Wilson, J. van Gestel, R.P. Sijbesma*, E. W. Meijer*: Amplification of Chirality in Benzene Tricarboxamide Supramolecular Polymers, Chem. Commun., 2006, 4404-4406. View Paper.
  107. H. Zhou, L. Baldini, J. Hong, A. J. Wilson, A. D. Hamilton*: Pattern Recognition of Proteins Based on an Array of Functionalised Porphyrins, J. Am. Chem. Soc., 2006, 128, 12833-12842. View Paper.
  108. A. J. Wilson, M. Masuda, R.P. Sijbesma*, E. W. Meijer*: Chiral Amplification in the Transcription of Supramolecular Helicity into a Polymer Backbone, Angew. Chem. Int. Ed. , 2005, 44, 2275-2279. View Paper.
  109. K. Groves, A. J. Wilson, A. D. Hamilton*: Catalytic Unfolding and Proteolysis of Cytochrome c Induced by Synthetic Binding Agents, J. Am. Chem. Soc., 2004, 126, 12833-12842. View Paper.
  110. D. A. Leigh*, A. Venturini, A. J. Wilson, J. K. Y. Wong, F. Zerbetto: The Mechanism of Formation of Amide-based Interlocked Compounds: Prediction of a New Rotaxane-Forming Motif, Chem. Eur. J., 2004, 10, 4960-4969. View Paper.
  111. L. Baldini, A. J. Wilson, J. Hong, A. D. Hamilton*: Pattern-Based Detection of Different Proteins Using an Array of Protein Surface Receptors, J. Am. Chem. Soc., 2004, 126, 5656-5657. View Paper.
  112. A. J. Wilson, M. Masuda, R. P. Sijbesma*, E. W. Meijer*: Covalent Fixation of Self-Assembled Architectures, Polymer Preprints, ACS Polymer Chemistry, 2003, 44, 2, 492-493.
  113. J. S. Hannam, T. J. Kidd, D. A. Leigh*, A. J. Wilson: “Magic Rod” Rotaxanes: The Hydrogen Bond-Directed Synthesis of Molecular Shuttles Under Thermodynamic Control , Org. Lett., 2003, 5, 1907-1910. View Paper.
  114. A. J. Wilson, K. Groves, R. K. Jain, H-S. Park, A. D. Hamilton*: Directed Denaturation: Room Temperature and Stoichiometric Unfolding of Cytochrome c by a Metalloporphryin Dimer, J. Am. Chem. Soc., 2003, 125, 4410-4421. View Paper.
  115. D. A. Leigh*, P. J. Lusby, S. J. Teat, A. J. Wilson, J. K. Y. Wong: Benzylic Imine Catenates: Readily Accessible Octahedral Analogues of the Sauvage Catenanes, Angew. Chem. Int. Ed. , 2001, 40, 1538-1543. View Paper.
  116. T. J. Kidd, D. A. Leigh*, A. J. Wilson: “Organic Magic Rings”: The Hydrogen Bond Directed Assembly of Catenanes Under Thermodynamic Control, J. Am. Chem. Soc., 1999, 121, 1599-1600. View Paper.

Books and Book Chapters

  1. A. J. Wilson*: α-Helix Mimetics as Inhibitors of Protein-Protein Interaction, in 'Inhibitors of Protein Protein Interactions', Editor A. Tavassoli, RSC, 2021, 305-335. View Paper.
  2. Editors: J. Jayawickramarajah, A. J. Wilson:Supramolecular Medicinal Chemistry and Chemical Biology, in 'Comprehensive Supramolecular Chemistry II', Ed in Chief, J Atwood, Elsevier, 2017, V, View Paper.
  3. Editors: A.J. Wilson, J. Jayawickramarajah:Bioinspired and Biomimetic Supramolecular Chemistry, in 'Comprehensive Supramolecular Chemistry II', Ed in Chief, J Atwood, Elsevier, 2017, IV, View Paper.
  4. A. J. Wilson*: Synthesis of peptidomimetic scaffolds, in 'Understanding and Exploiting Protein–Protein Interactions as Drug Targets', Ed. G. Zinzalla, Future Science Ltd eBook, 2013, 74-89. View Paper.
  5. A.J.Wilson*: Hydrogen Bonding Receptors for Molecular Guests , in ‘Supramolecular Chemistry: From Molecules to Nanomaterials’ Vol 3, Ed. Enrique García-España , Series Eds. P.A . Gale, J. W. Steed, Wiley, 2012, 1325-1344. View Paper.

Contributions to Annual Volumes

  1. A.J.Wilson*: Supramolecular Chemistry, Annu. Rep. Prog. Chem., Sect. B, Org. Chem., 2008, 104, 164-183. View Paper.
  2. A.J.Wilson*: Supramolecular Chemistry, Annu. Rep. Prog. Chem., Sect. B, Org. Chem., 2007, 103, 174-192. View Paper.
  3. A.J.Wilson*: Supramolecular Chemistry, Annu. Rep. Prog. Chem., Sect. B, Org. Chem., 2006, 102, 148-167. View Paper.

Invited and Contributed Commentaries

  1. A. J. Wilson, P. Gunning*: Understanding Protein–Protein Interactions: Essential Players in (Patho)physiology (Part 2), ChemMedChem, 2016, 11, 732-733. View Paper.
  2. A. J. Wilson*, P. Gunning: Understanding Protein--Protein Interactions: Essential Players in (Patho)physiology (Part 1), ChemBioChem, 2016, 17, 644-645. View Paper.
  3. S. Thompson, A. J. Wilson, A. R. Battersby:In celebration of the 60th birthday of Professor Andrew D. Hamilton FRS, Org. Biomol. Chem., 2013, 11, 6236-6241. View Paper.
  4. A. J.Wilson*: Hydrogen bonding: Attractive arrays, Nature Chem., 2011, 3, 193-194. View Paper.
  5. A.J.Wilson*: Dynamic Combinatorial Chemistry, Angew. Chem. Int. Ed. , 2010, 49, 4011-4011. View Paper.
  6. A.J.Wilson*: Chemical sensing: Nanonose for sniffing out proteins , Nature Chem., 2009, 1, 429-430. View Paper.
  7. R. S. Grainger*, A. J. Wilson*: The Bürgenstock 41st EUCHEM Conference on Stereochemistry, Chem. Commun., 2006, 3269-3272. View Paper.

Published Abstracts

  1. A. J. Wilson*: Peptide-Based Inhibitors of Protein-Protein Interactions: Biophysical, Structural and Cellular Consequences of Introducing a Constraint , J. Pept. Sci., 2022, P214. View Paper.
  2. P. Zhang, A. J. Wilson*: Discovery of Stapled Peptides as Efficient BCL-xL Inhibitors, Proceedings of the 36th European Peptide Symposium, 2022, P107 and https://doi.org/10.17952/36EPS.2022.101. View Paper.
  3. Y. Li, S. L. Warriner, A. J. Wilson*: Discovery of Internal Ligand Inhibitors Targeting SHANK1 PDZ Domain Guided by Dynamic Ligation Screening Strategy, Proceedings of the 36th European Peptide Symposium, 2022, P108 and https://doi.org/10.17952/36EPS.2022.103. View Paper.
  4. A. Wilson: Development and Exploitation of Photo-Crosslinking Methodology to Study Protein-Protein Interactions, J. Pept. Sci., 2018, 24, S49-50. View Paper.
  5. P. Rowell, J. Miles, A. Wilson, T. Edwards: Novel Methods for Modulating the Activity of Bcl-2 Family Proteins in Apoptosis, FEBS J,, 2016, 283, P02.02.2053 doi:10.1111/febs.13808. View Paper.
  6. V. Azzarito, S. L. Warriner, A. J. Wilson*:Oligobenzamide Alpha-Helix Mimetic Scaffolds: The Role of Non-Covalent Interactions in Molecular Recognition, Abs. Pap. Am. Chem. Soc. , 2013, 245, 292_ORGN.
  7. A. J. Wilson*, A. Gooch M. J. Pelizzarro A. M. McGhee C. A. Kilner: Hydrogen-Bonding Building Blocks for Supramolecular Polymer Assembly, Abs. Pap. Am. Chem. Soc. , 2010, 239, 347-PMSE.
  8. A. Gooch, A. M. McGhee, C. I. Lindsay, A. J. Wilson*: Towards Stimuli-Responsive Self-Assembling Materials Based On Novel Triple Hydrogen Bonding Arrays, Abs. Pap. Am. Chem. Soc. , 2010, 239, 779-ORGN.
  9. M. L. Pellizaro, C. Kilner, A. J. Wilson*: Effects of Pre-Organisation On The Binding Affinity Of DDA-AAD Hydrogen Bond Arrays, Abs. Pap. Am. Chem. Soc. , 2010, 239, 765-ORGN.
  10. A. J. Wilson*, A. E. Ashcroft, J. Muldoon, M. Filby: Selective Protein-Surface Sensing Using Ruthenium (II) Tris-(Bipyridine) Complexes, Abs. Pap. Am. Chem. Soc. , 2010, 239, 332-POLY.
  11. F. Campbell, B. Malkova, T. A. Edwards, A. J. Wilson*: Novel Oligoamide Foldamers For The Disruption Of Selected Protein-Protein Interactions, Abs. Pap. Am. Chem. Soc. , 2008, 235, 432-ORGN.
  12. F Campbell, Jeffrey Plante, Barbora Malkova and A. J. Wilson*: Sequence Specific Syntheses Of N And O-Alkylated Aromatic Oligoamide Foldamers, Abs. Pap. Am. Chem. Soc. , 2007, 234, 089-ORGN.
  13. A. M. McGhee and A. J. Wilson*: Formation Of Heterodimers Using Linear Arrays Comprising Three Hydrogen-Bonding Sites, Abs. Pap. Am. Chem. Soc. , 2007, 234, 191-ORGN.
  14. E. W. Meijer*, R. P. Sijbesma, A. J. Wilson, M. Masuda, and P. Jonkheijm: Covalent Fixation Of Self-Assembled Architectures, Abs. Pap. Am. Chem. Soc. , 2003, 226, 573-POLY.
  15. J. K. Y. Wong, D. A. Leigh*, F. G. Gatti, A. J. Wilson: Spaced Out Binding Sites: Structural Requirements For The Hydrogen Bond-Directed Assembly Of Rotaxanes, Abs. Pap. Am. Chem. Soc. , 2002, 224, 319-ORGN.
  16. A. J. Wilson, A. D. Hamilton: Protein Surface Recognition Using Designed Molecules, Abs. Pap. Am. Chem. Soc. , 2002, 224, 196-ORGN.
  17. A. J. Wilson, R. K. Jain, H-S. Park, A. D. Hamilton: Designing Denaturants: Metalloporphyrin Derivatives That Denature Proteins At Room Temperature And Physiological Ph, Abs. Pap. Am. Chem. Soc. , 2002, 224, 273-ORGN.
  18. D. A. Leigh*, A. J. Wilson, A. M. Z. Slawin, T. J. Kidd: Non-Covalent Recognition of a Functional Group Type: The Selective Binding of Secondary Amides by Benzylic Amide Macrocycles, Abs. Pap. Am. Chem. Soc. , 1999, 218, 115-ORGN.
  19. D. A. Leigh*, T. J. Kidd, A. J. Wilson: "Organic Magic Rods": The Hydrogen Bond Directed Assembly of Rotaxanes Under Thermodynamic Control, Abs. Pap. Am. Chem. Soc. , 1999, 218, 234-ORGN.